Royal Air Force Typhoon FGR4s have conducted a mission with French warplanes in a joint strike on an hidden munitions depot in Syria used by the IS group, as stated by the British defence ministry.
The facility, located using surveillance, was assessed as housing weapons and explosive materials, the announcement noted, and was located in hills just above the historic site of Palmyra in the heart of Syria.
"Our fighter planes utilized Paveway IV guided bombs to strike a number of approach shafts down to the site... preliminary assessments indicate the objective was successfully hit," the MoD said.
There was no sign of any civilian impact in the strike conducted Saturday night and each participating jet returned to base without incident, the ministry further stated.
The Typhoon FGR4s were assisted by a Voyager aerial refuelling aircraft.
The Islamic State group - also known as Daesh - enforced extremist governance over parts of both Syria and Iraq until 2019.
"This strike underscores our UK leadership, and resolve to work closely with our allies, to stamp out any re-emergence of the terrorist group and their violent and radical beliefs in the Middle East," the British Defence Secretary John Healey remarked.
UK warplanes have conducted overwatch operations over Syrian airspace to "prevent any attempted comeback" of the group after its defeat at the battle of Baghuz in the year 2019, the ministry said.
"I want to thank every member of our armed forces involved in this operation for their professionalism and their valour," Healey added. "They were among numerous British personnel stationed over the holidays. This mission, to remove militants who pose a risk to our safety, shows how British military are prepared to act, all year round, protecting the UK at home and powerful internationally."
Last December, the United States armed forces conducted what it described as a "major assault" on Daesh sites in the country, following an ambush claimed the lives of two American soldiers and a civilian interpreter in Palmyra.
The United Nations reports IS still maintains between 5,000 and 7,000 combatants in Syria and Iraq.